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for Eyelid and Facial Plastic Surgery

Dr. Kevin Perman


Phone (301) 571-0000
6420 Rockledge Drive, Suite 4300 | Bethesda MD 20817


Botox, Xeomin and Dysport are classified as neurotoxins. They offer temporary wrinkle relief most efficiently in the upper third of the face (forehead, eyebrows and eyelids) for upwards of 3-5 months. In the greater Washingtion D.C. Virginia, Maryland area, our practice boasts the longest clinical experience with facial botox, dating back to 1983. Dr. Perman was a member of the clinical investigation group at UCLA Medical Center when oculinum toxin was a research drug prior to its attaining FDA approval. Drs. Perman and Cytryn have taught numerous physicians, both in the U.S. and abroad in the techniques of neurotoxin injections. Patients seek out our expertise for treatment of facial rhytids.

What is XEOMIN?

XEOMIN is a botulinum toxin that is used to treat adults with cervical dystonia and blepharospasm. It has been used around the world since 2005 and was introduced to the US market in 2010 by Merz Pharmaceuticals, LLC.  

·       To treat adults with cervical dystonia to decrease the severity of abnormal head position and neck pain  

·       To treat abnormal spasm of the eyelids (blepharospasm) in adults who have had prior treatment with onabotulinumtoxinA (Botox®) 



XEOMIN proveded by The Center for Eyelid and Facial Plastic Surgery in Bethesda MD
Click Here to Visit the Xeomin Website

Botulinum toxin is a naturally occurring protein produced by the bacteria Clostridium botulinum. Botulinum toxin type A—the active ingredient in XEOMIN—is produced commercially from C. botulinum serotype A.

XEOMIN is injected into muscles to decrease their activity.

XEOMIN blocks the release of a chemical messenger—acetylcholine—that conveys the signal from nerve terminals and causes muscle fibers to contract. Not all terminals are affected by botulinum toxin, so the muscles can still contract, just less forcefully. This allows the muscles to contract more normally.

Not all botulinum toxin products are the same. This is reflected in the unique names for each product. The dose of XEOMIN may be different from other botulinum toxin products. 

In nature, C. botulinum produces the toxin in association with accessory proteins (toxin complex). Merz takes the toxin complex and employs a proprietary manufacturing process that isolates the therapeutic component and removes the accessory proteins to produce XEOMIN.